The following represents an incomplete list of items about general anesthetics
2008
2006
2004
2003
2002
"Folding of a de novo Designed Native-like Four-helix Bundle Protein," Alex Chapeaurouge, Jonas S. Johansson and Sergio T. Ferreira, Journal of Biological Chamistry, 277 16478-16483.
2000
" A Designed Four-alpha-Helix Bundle That Binds the Volatile General Anesthetic Halothane with High Affinity," Jonas S. Johansson, Daphna Scharf, Lowri A. Davies, Konda S. Reddy, and Roderic G. Eckenhoff, Biophys. J., 78 982-993.
1998
"A Designed Cavity in the Hydrophobic Core of a Four-alpha-Helix Bundle Improves Volatile Anesthetic Binding Affinity," Jonas S. Johansson, Brian R. Gibney, Francesc Rabanal, Konda S. Reddy, and P. Leslie Dutton, Biochemistry, 37, 1421-1429, 1998.
"A Native-Like Three-alpha-Helix Bundle Protein from Structure-Based Redesign: A Novel Maquette Scaffold," Jonas S. Johansson, Brian R. Gibney, Jack J. Skalicky, A. Joshua Wand, and P. Leslie Dutton, JACS, 120, 3881 -3886, 1988.
"Do Specific or Nonspecific Interactions with Proteins Underlie Inhalational Anesthetic Action?" Eckenhoff, R. G., Mol. Pharmacol., 54, 610-615.
1997
"Interactions between Inhaled Anesthetics and Proteins," Eckenhoff, R. G. and Johansson, J. S., Pharmacol. Rev., 49, 343-367.
1994
"Molecular and Cellular Mechanisms of General Anesthesia,"
Franks, N. P. and Lieb, W. R., Nature, 367,
607-614.
additional background
Some useful general background on fluorescence and quenching is available on the
Web from Prof. Gabor Mocz.